Orforglipron — Certificate of Analysis

Lab Results › Orforglipron

Orforglipron

Batch BH-260227

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99.68%
Purity
✓ Endotoxin Cleared

Independently verified by accredited third-party laboratory — Certificate of Analysis on file

Sample Summary

Product Orforglipron
Compound LY3502970; non-peptide small-molecule GLP-1 receptor agonist
CAS Number 2381403-34-3
Molecular Weight 548.60 Da
Batch / Lot BH-260227
Accession # BH2602270001
Test Date February 27, 2026
Appearance White to Off-White Powder
Identity Method LC-MS
Endotoxin (LAL) < 1.0 EU/mg
Purity Method HPLC-UV

Purity Analysis

Method: HPLC-UV with LC-MS Confirmation

99.68
% Purity

Orforglipron confirmed via LC-MS. Small molecule GLP-1 receptor agonist confirmed. Non-peptide structure verified. Molecular weight: 548.60 Da.

Full Certificate PDF

A signed Certificate of Analysis from our accredited third-party laboratory is on file for batch BH-260227. To receive the full PDF documentation, submit a request using the link below.

Request Batch COA PDF →

Requests are fulfilled within one business day. Include your research institution or laboratory name for expedited processing.

Test History

99.68%
Average Purity
99.68% – 99.68%
Purity Range
2
Tests Conducted
All Cleared
Endotoxin Status

Entries below reflect pre-launch quality validation runs conducted during our 2024–2025 R&D and inventory build phase. Current inventory is assigned batch code BH-260227.

Batch Date Purity Endotoxin
BH-250523 May 2025 99.68% Cleared
BH-260227 Feb 2026 99.3% ClearedLatest

Frequently Asked Questions

What does HPLC-UV testing measure?

High-Performance Liquid Chromatography with UV detection (HPLC-UV) separates the compound from potential impurities using a liquid mobile phase. The UV detector measures absorbance at a target wavelength, allowing precise quantification of the target compound and any co-eluting species. Purity is expressed as the area percentage of the main peak relative to all detected peaks.

Why is LC-MS confirmation important?

Liquid Chromatography–Mass Spectrometry (LC-MS) provides definitive identity confirmation by measuring the exact molecular mass of the compound. This rules out isobaric impurities and confirms that the compound detected by HPLC-UV is the correct target molecule — not a structurally similar analogue.

What is the USP <85> endotoxin standard?

The United States Pharmacopeia Chapter <85> Bacterial Endotoxin Test (BET) defines limits for endotoxin contamination in injectable and research-grade materials. Passing this test confirms that endotoxin levels fall below the threshold that would compromise experimental validity in cell-based or in vivo research models.

How often are batches re-tested?

Every new production batch is independently tested before release. We do not rely on retest data from prior batches — each lot receives its own Certificate of Analysis. Historical test results are published above for full transparency.