Oral peptides are short-chain amino acid sequences — typically 2 to 20 amino acids in length — formulated for absorption through the gastrointestinal tract rather than by injection. Traditional research peptides require subcutaneous or intramuscular injection because the stomach’s acidic environment and digestive enzymes break most peptides down before they reach systemic circulation. Oral peptide formulations address this through enteric encapsulation, which protects the compound from gastric acid and releases it at intestinal pH where absorption can occur.

Injectable peptides require reconstitution from lyophilised powder, sterile water, cold storage, and needle administration. Oral capsules require none of these. The key pharmacological consideration is bioavailability: injectable administration achieves near-100% systemic availability, while oral delivery requires engineered encapsulation to achieve meaningful absorption. Biohacker’s formulations are validated against injectable reference standards for each compound class. For research applications where dosing consistency and administration convenience are priorities, oral capsule format offers a materially different protocol experience.

BPC-157 is a pentadecapeptide that demonstrates acid stability under gastric conditions — an unusual property that makes it a particularly suitable candidate for oral delivery. Preclinical research has documented systemic activity following oral administration, including the same tissue repair and cytoprotective effects observed in injection studies. Biohacker’s BPC-157 capsules are enteric-coated to provide additional protection through the gastric phase and validated for intestinal absorption. Research on oral BPC-157 continues to expand; the available literature supports the oral route as a viable research delivery method for this specific compound.

Research-grade peptides are generally held to a minimum 98% purity standard, with high-quality suppliers targeting 99% or above. Below 98%, the impurity fraction — which consists of truncated sequences, oxidised forms, or synthesis byproducts — is large enough to introduce confounding variables in research applications. Biohacker requires a minimum 99% purity floor across all compounds, verified by HPLC analysis conducted by independent third-party laboratories. Average purity across the catalogue is 99.67%. Each batch is tested individually — purity is not inferred from previous lots.

Every production lot is sent to an accredited independent laboratory for a three-part analysis: (1) HPLC purity testing, which measures the concentration of the target compound relative to all detected species; (2) ESI-MS mass confirmation, which verifies the molecular weight matches the expected compound; (3) endotoxin testing to USP <85> standards, confirming the absence of bacterial contamination above threshold. No compound ships until all three pass. The resulting Certificate of Analysis — including batch number, test date, purity percentage, and endotoxin status — is published on the Biohacker COA page and traceable by lot number.

A Certificate of Analysis (COA) is a formal laboratory document that records the analytical testing results for a specific production batch of a compound. For research peptides, a credible COA should include: the compound name and CAS number, the batch or lot number, the test date, the purity percentage as determined by HPLC, the mass confirmation result from mass spectrometry, and endotoxin testing results. Biohacker publishes batch-level COAs for every compound in the catalogue. You can access them at biohacker.dev-up.click/coas/ and verify any order against its specific production lot by lot number.

Most peptides are degraded in the stomach before they reach the small intestine, where absorption would otherwise occur. Two barriers prevent oral peptide absorption: (1) low gastric pH, which denatures many peptide structures, and (2) peptidase enzymes that cleave peptide bonds. Enteric encapsulation addresses the first barrier by protecting the compound through the gastric phase and triggering dissolution at duodenal pH. Permeation enhancers address the second by improving the compound’s ability to cross the intestinal epithelium. Not all peptides are equally amenable to oral delivery — Biohacker formulates each compound class individually, and only compounds with validated oral absorption profiles are listed in the catalogue.

BPC-157 (Body Protection Compound 157) has the most extensive research literature in the context of gastrointestinal health. Derived from a protein found in human gastric juice, it has been studied in models of colitis, gastric ulcers, intestinal fistulas, and inflammatory bowel disease, with documented cytoprotective and anti-inflammatory effects across multiple GI tissue types. Over 80 preclinical publications cover its GI applications. GHK-Cu, a copper peptide with potent tissue remodelling activity, is also studied in the context of mucosal repair. Both are available in oral capsule format from Biohacker.

The most active compounds in longevity and anti-aging research include: Epithalon, a tetrapeptide documented to stimulate telomerase activity and extend telomere length in human somatic cells; MOTS-c, a mitochondrial-derived peptide that regulates metabolic pathways associated with aging and has demonstrated lifespan extension in animal models; GHK-Cu, a copper-binding tripeptide with broad tissue regeneration activity and regulation of over 4,000 human genes including longevity-related pathways; and NAD+, the coenzyme central to sirtuin activation and DNA repair. All four are available in the Biohacker catalogue.

Yes. Biohacker ships research compounds within the United States. Orders are dispatched same day as QA clearance. All compounds are shipped in discreet, tamper-evident packaging with the Certificate of Analysis included. Research compounds are sold strictly for laboratory and scientific research purposes and are not for human or veterinary use.

Pharmaceutical-grade compounds are manufactured under GMP (Good Manufacturing Practice) conditions regulated by the FDA or equivalent authority, intended for human administration, and held to strict documentation standards. Research-grade compounds are produced for laboratory and scientific research use, not for human administration. They are held to high purity standards — typically 98–99%+ HPLC purity — and independently third-party tested, but are not manufactured under pharmaceutical GMP regulations. Biohacker’s compounds are research-grade: verified to 99%+ purity with full batch COA documentation, supplied strictly for research use only.

Enteric encapsulation uses a polymer coating that resists low-pH gastric acid but dissolves at the higher pH found in the small intestine (approximately pH 5.5–6.0 at the duodenum). This protects acid-sensitive compounds from degradation in the stomach and ensures they reach the intestine intact, where absorption can occur. For oral peptide delivery, enteric encapsulation is not optional — most peptides exposed to gastric acid (pH 1.5–3.5) without protection are fully hydrolysed before reaching the absorptive surface of the gut. Biohacker formulates enteric coatings per compound class, selecting polymer grades and coating weights appropriate for each peptide’s stability profile.

All Biohacker products are supplied in 60-capsule bottles. Capsule count is standardised across the catalogue to simplify research protocol design. Each bottle carries the lot number linking to the corresponding Certificate of Analysis, verifiable on the COA page.

Every Biohacker shipment carries a lot number on the packaging. You can reference this lot number on the COA page to access the independent laboratory Certificate of Analysis for that specific production batch. The COA records HPLC purity, mass spectrometry confirmation, endotoxin result, batch number, and test date. If you wish to conduct independent verification, the lot number can be referenced when submitting a sample to a third-party analytical laboratory.

No. All Biohacker compounds are strictly for laboratory and scientific research use only. They are not intended for, and must not be used for, human or veterinary consumption, clinical application, or diagnostic purposes. By purchasing from Biohacker, buyers confirm that products are acquired for research purposes only and that they are 18 years of age or older. Biohacker does not provide dosing guidance, medical advice, or administration protocols.