Quietly, the inflammation stops.

KPV (Lys-Pro-Val) is a tripeptide representing the C-terminal sequence of alpha-melanocyte-stimulating hormone (α-MSH). It is the minimal active fragment of α-MSH responsible for its anti-inflammatory properties, and it acts through melanocortin-1 receptor (MC1R) signalling to suppress NF-κB activation — the master regulator of inflammatory cytokine production. KPV demonstrates significant potency in inflammatory models despite its small size, and unlike full-length α-MSH, it does not carry tanning/pigmentation activity (which requires the N-terminal tripeptide His-Phe-Arg-Trp).

Subcutaneous lyophilised formulation. Pharmacokinetic parameters validated by HPLC-MS at our Lausanne reference lab.

Every BIOHACKER batch ships with a third-party HPLC-MS certificate signed by the Lausanne reference lab.

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