Pyridine dinucleotide · Sirtuin & PARP substrate
Sirtuin fuel.
Delivered intact.
Nicotinamide adenine dinucleotide (NAD+) is the central redox coenzyme of every living cell and the obligate substrate for the sirtuin (SIRT1–7) and PARP enzyme families. Tissue NAD+ falls roughly 50% between young adulthood and senescence — one of the metabolic hallmarks of ageing — as the NAMPT salvage pathway slows and CD38 consumption climbs. Orally administered NAD+ is almost entirely hydrolysed in the gut, with under 5% reaching circulation intact; the subcutaneous lyophilised format bypasses first-pass gut metabolism to present the intact coenzyme directly to the sirtuin and PARP axes — the reason parenteral delivery has become the format of interest in NAD+ research.
Subcutaneous lyophilised formulation. Pharmacokinetic parameters validated by HPLC-MS at our Lausanne reference lab.
Every BIOHACKER batch ships with a third-party HPLC-MS certificate signed by the Lausanne reference lab.
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